South Africa Travel Vaccines & Health
Key Highlights: Cape Town, Garden Route, Kruger National Park safaris, vineyards, shark diving
Book clinic visits 6 to 8 weeks before departure to complete multi-dose courses (e.g. Rabies, Hep B).
Health Summary for UK Travellers
World-class private healthcare in Cape Town and Johannesburg, but high malaria risk in Kruger Park and northeastern game reserves.
Yellow Fever Certificate Requirement
Strictly enforced: Certificate is legally mandatory for all travellers aged 1 year or older arriving from or transiting (>12 hours) through yellow fever endemic countries in Africa or South America.
Malaria Risk Advisory
Mosquito Prevention RequiredAffected Areas: Kruger National Park, northeastern Mpumalanga, northern and eastern Limpopo, and northeastern KwaZulu-Natal.
Seasonal risk from September to May. Antimalarial tablets (Atovaquone/Proguanil or Doxycycline) are recommended for safari travel in Kruger and surrounding private game reserves. Cape Town, the Garden Route, and Johannesburg are malaria-free.
Recommended Vaccines for Most Travellers
Strongly advised by UK travel health authorities for holidays, city visits, and general tourist itineraries.
Why it's advised: Recommended for most UK travellers.
| Provider / Travel Clinic | Course / Dosage | Price | BookBook / View |
|---|---|---|---|
 Parkview Pharmacy Child Single Dose | Child Single Dose | £35.00 Best Price | View Offer |
 Murray's PharmacyClinic Single Dose | Single Dose | £45.00 | Book Clinic |
 Ealing Travel Clinic Single Dose | Single Dose | £45.00 | View Offer |
 TravelDoc Single Dose | Single Dose | £50.00 | View Offer |
Parkview Pharmacy Single Dose | Single Dose | £50.00 | View Offer |
 Regent Street Clinic™Clinic Single Dose | Single Dose | £50.00 | Book Clinic |
 Well Pharmacy Single Dose | Single Dose | £59.00 | View Offer |
 MASTA Travel HealthClinic Single Dose | Single Dose | £63.00 | Book Clinic |
MASTA Travel HealthClinic Child Single Dose | Child Single Dose | £63.00 | Book Clinic |
 Nomad TravelClinic Single Dose | Single Dose | £63.00 | Book Clinic |
Nomad TravelClinic Child Single Dose | Child Single Dose | £63.00 | Book Clinic |
 Boots Travel VaccinationClinic Single Dose | Single Dose | £65.00 | Book Clinic |
 Superdrug Health ClinicClinic Single Dose | Single Dose | £67.00 | Book Clinic |
 London Vaccination Clinic Child Single Dose | Child Single Dose | £70.00 | View Offer |
London Vaccination Clinic Single Dose | Single Dose | £89.00 | View Offer |
MASTA Travel HealthClinic 2-Dose Course | 2-Dose Course | £126.00 | Book Clinic |
Superdrug Health ClinicClinic 2-Dose Course | 2-Dose Course | £134.00 | Book Clinic |
Why it's advised: Ensure 10-year booster is current.
| Provider / Travel Clinic | Course / Dosage | Price | BookBook / View |
|---|---|---|---|
Parkview Pharmacy Single Dose | Single Dose | £28.00 Best Price | View Offer |
TravelDoc Single Dose | Single Dose | £30.00 | View Offer |
Ealing Travel Clinic Single Dose | Single Dose | £30.00 | View Offer |
Regent Street Clinic™Clinic Single Dose | Single Dose | £30.00 | Book Clinic |
Well Pharmacy Single Dose | Single Dose | £35.00 | View Offer |
MASTA Travel HealthClinic Single Dose | Single Dose | £40.00 | Book Clinic |
Boots Travel VaccinationClinic Single Dose | Single Dose | £40.00 | Book Clinic |
Nomad TravelClinic Single Dose | Single Dose | £40.00 | Book Clinic |
Superdrug Health ClinicClinic Single Dose | Single Dose | £42.00 | Book Clinic |
Murray's PharmacyClinic Single Dose | Single Dose | £45.00 | Book Clinic |
London Vaccination Clinic Single Dose | Single Dose | £50.00 | View Offer |
Consider for Specific Activities or Extended Stays
Recommended if trekking, visiting rural farming areas, handling animals, or staying with friends/relatives for more than 2 weeks.
Why it's advised: Recommended if visiting informal settlements or rural communities.
| Provider / Travel Clinic | Course / Dosage | Price | BookBook / View |
|---|---|---|---|
TravelDoc Single Dose | Single Dose | £30.00 Best Price | View Offer |
Ealing Travel Clinic Single Dose | Single Dose | £30.00 Best Price | View Offer |
Regent Street Clinic™Clinic Single Dose | Single Dose | £30.00 Best Price | Book Clinic |
Parkview Pharmacy Single Dose | Single Dose | £32.50 | View Offer |
 Day Lewis Pharmacy Single Dose | Single Dose | £34.00 | View Offer |
Murray's PharmacyClinic Single Dose | Single Dose | £35.00 | Book Clinic |
Well Pharmacy Single Dose | Single Dose | £35.00 | View Offer |
Well Pharmacy 3-Dose Course | 3-Dose Course | £36.00 | View Offer |
MASTA Travel HealthClinic Single Dose | Single Dose | £38.00 | Book Clinic |
Nomad TravelClinic Single Dose | Single Dose | £38.00 | Book Clinic |
Boots Travel VaccinationClinic Single Dose | Single Dose | £40.00 | Book Clinic |
Superdrug Health ClinicClinic Single Dose | Single Dose | £42.00 | Book Clinic |
London Vaccination Clinic Single Dose | Single Dose | £66.00 | View Offer |
Why it's advised: Recommended for wildlife rangers or remote game park stays.
| Provider / Travel Clinic | Course / Dosage | Price | BookBook / View |
|---|---|---|---|
Murray's PharmacyClinic Single Dose | Single Dose | £55.00 Best Price | Book Clinic |
Regent Street Clinic™Clinic Single Dose | Single Dose | £65.00 | Book Clinic |
London Vaccination Clinic Single Dose | Single Dose | £66.00 | View Offer |
TravelDoc Single Dose | Single Dose | £75.00 | View Offer |
Parkview Pharmacy Single Dose | Single Dose | £75.50 | View Offer |
Boots Travel VaccinationClinic Single Dose | Single Dose | £80.00 | Book Clinic |
Ealing Travel Clinic Single Dose | Single Dose | £90.00 | View Offer |
Murray's PharmacyClinic 3-Dose Course | 3-Dose Course | £175.00 | Book Clinic |
Ealing Travel Clinic 2-Dose Course | 2-Dose Course | £180.00 | View Offer |
Well Pharmacy 3-Dose Course | 3-Dose Course | £222.00 | View Offer |
TravelDoc 3-Dose Course | 3-Dose Course | £225.00 | View Offer |
Parkview Pharmacy 3-Dose Course | 3-Dose Course | £226.50 | View Offer |
Boots Travel VaccinationClinic 3-Dose Course | 3-Dose Course | £240.00 | Book Clinic |
Why it's advised: High local prevalence. Recommended for extended visits.
| Provider / Travel Clinic | Course / Dosage | Price | BookBook / View |
|---|---|---|---|
Boots Travel VaccinationClinic Child Single Dose | Child Single Dose | £27.00 Best Price | Book Clinic |
Parkview Pharmacy Child Single Dose | Child Single Dose | £30.00 | View Offer |
Ealing Travel Clinic Single Dose | Single Dose | £40.00 | View Offer |
Murray's PharmacyClinic Single Dose | Single Dose | £45.00 | Book Clinic |
MASTA Travel HealthClinic Child Single Dose | Child Single Dose | £45.00 | Book Clinic |
Nomad TravelClinic Child Single Dose | Child Single Dose | £45.00 | Book Clinic |
TravelDoc Single Dose | Single Dose | £45.00 | View Offer |
Regent Street Clinic™Clinic Single Dose | Single Dose | £45.00 | Book Clinic |
Parkview Pharmacy Single Dose | Single Dose | £50.00 | View Offer |
MASTA Travel HealthClinic Single Dose | Single Dose | £52.00 | Book Clinic |
Superdrug Health ClinicClinic Single Dose | Single Dose | £52.00 | Book Clinic |
Boots Travel VaccinationClinic Single Dose | Single Dose | £52.00 | Book Clinic |
Nomad TravelClinic Single Dose | Single Dose | £52.00 | Book Clinic |
London Vaccination Clinic Child Single Dose | Child Single Dose | £55.00 | View Offer |
London Vaccination Clinic Single Dose | Single Dose | £66.00 | View Offer |
Boots Travel VaccinationClinic Child 3-Dose Course | Child 3-Dose Course | £81.00 | Book Clinic |
Parkview Pharmacy Child 3-Dose Course | Child 3-Dose Course | £90.00 | View Offer |
Murray's PharmacyClinic 3-Dose Course | 3-Dose Course | £120.00 | Book Clinic |
Ealing Travel Clinic 3-Dose Course | 3-Dose Course | £120.00 | View Offer |
MASTA Travel HealthClinic Child 3-Dose Course | Child 3-Dose Course | £135.00 | Book Clinic |
Nomad TravelClinic Child 3-Dose Course | Child 3-Dose Course | £135.00 | Book Clinic |
Superdrug Health ClinicClinic 3-Dose Course | 3-Dose Course | £150.00 | Book Clinic |
Well Pharmacy 3-Dose Course | 3-Dose Course | £150.00 | View Offer |
Parkview Pharmacy 3-Dose Course | 3-Dose Course | £150.00 | View Offer |
MASTA Travel HealthClinic 3-Dose Course | 3-Dose Course | £156.00 | Book Clinic |
Boots Travel VaccinationClinic 3-Dose Course | 3-Dose Course | £156.00 | Book Clinic |
Nomad TravelClinic 3-Dose Course | 3-Dose Course | £156.00 | Book Clinic |
London Vaccination Clinic Child 3-Dose Course | Child 3-Dose Course | £165.00 | View Offer |
London Vaccination Clinic 3-Dose Course | 3-Dose Course | £198.00 | View Offer |
Malaria cannot be prevented by vaccination. Travellers visiting risk zones should take preventive antimalarial tablets and practice bite avoidance (DEET 50% repellent, treated mosquito nets, long-sleeved clothing).
Generic Atovaquone / Proguanil
From £19.95Taken once daily starting 1–2 days before entering a malaria zone, during the stay, and for 7 days after leaving.
Malarone (branded)
From £24.80Taken once daily starting 1–2 days before entering a malaria zone, during the stay, and for 7 days after leaving.
Doxycycline (Antimalarial)
From £11.75Taken daily starting 1–2 days before entering, during the stay, and for 4 weeks after leaving.
Lariam (Mefloquine)
From £24.99Usually started before travel and taken weekly; suitability and timing must be assessed by a clinician.
NaTHNaC TravelHealthPro
Country guidance can change. Check the source and speak with a qualified travel-health professional before booking.